The University of Piraeus Research Center (UPRC) facilitates the research activities of university members in different programmes and initiatives. In this context, the Department of Informatics (through UPRC) has been actively involved in a significant number of (i) EU funded R&D projects, (ii) National projects funded by the Greek Ministry of Development and the General Secretariat of Research and Technology, and (iii) Projects developed in collaboration with enterprises (both international and national).

The Data Science Lab @ Univ. Piraeus (est. 2015), aims to advance research on a wide range of Data Science topics, including big data management, statistics and data analytics, machine learning, and semantic integration, with particular interest in mobility data.